Citation of Professor Pranab kumar Bhttacharya at Journal Oncology Letter

                 ONCOLOGY LETTERS 7: 583-587, 2014

Salivary gland tumors: A 20‑year review of clinical

diagnostic accuracy at a single center

WEI HAN LEE,Te-Ming TsengHsin-Te HsuFei-Peng LeeShih-Han HungPo-Yueh Chen

A Abstract.

Obtaining reliable preoperative diagnosis is crucialin planning treatment for patients with salivary gland tumors.the purpose of this study was to evaluate the accuracy of

preoperative clinical diagnosis of salivary gland tumors managed at a single tertiary university hospital over a period of 20 years. A retrospective analysis of the period between

1992 and 2011 was carried out to review the cases of patients with salivary gland tumors. A total of 101 patients wereenrolled and general data were described. Clinical diagnosis was compared with the final pathological diagnosis to reveal the clinical diagnostic accuracy. Of the parotid and subman dibular gland tumor  86 and 67% were benign, respectively.  The clinical diagnostic accuracies for diagnosis of parotid tumors as benign or malignant were 100 and 57% respectively.

The clinical diagnostic accuracies for diagnosis of submandibular tumors as benign or malignant were 67%. Therefore, the overall clinical judgment of benign and malignant tumors in the submandibular gland is unreliable. The accuracy for a parotid tumor to be clinically interpreted as benign was 100%. While it is difficult to draw any conclusion for non‑parotid gland tumors, surgical intervention should be recommended in patients with parotid tumors clinically suspected to be malign ant, and all submandibular, sublingual and minor salivary land tumors.

Introduction

The m most common type of salivary gland tumor is  slow growing benign tumor of the parotid gland. The most commonly observed clinical presentation is the appearance

of a symptomless mass or lump over the affected area. Less often, signs include fluid draining from the ear, pain, numness, weakness and trouble swallowing. However, lump formation or swelling of the salivary glands can also originatefrom non neoplastic causes, including infection, sialolithiasis, arcoidosis, amyloidosis and Sjogren syndrome. Salivarygland cancers are rare, comprising only 2% of head and neck tumors. According to the latest data released by the Taiwan Bureau of Health Promotion, the incidence of salivary gland neoplasia is ~1.18

cases per 100,000 individuals in Taiwan. In 2009, 55 ortalities ( 0.32 per 100,00 m ales and 0.16

per 100,000females) associated with salivary gland tumors

1

Department of Otolaryngology, Head and Neck Surgery, Taipei Medical University

Shuang Ho Hospital;

2

Department of Otolaryngology, Taipei Medical University Hospital, Taipei 110;

3

Department of Otolaryngology, School of Medicine, Taipei Medical University, Taipei 235, Taiwan, R.O.C.

Received June 28, 2013; Accepted December 4, 2013

DOI: 10.3892/ol.2013.1750

Salivary gland tumors: A 20-year review of clinical diagnostic accuracy at a single center. Available from: https://www.researchgate.net/publication/259608854_Salivary_gland_tumors_A_20-year_review_of_clinical_diagnostic_accuracy_at_a_single_center [accessed Sep 2, 2015].

 Citation No 9   Chakraboty S  Bera S  Bhattacharya PK "salivary gland lesions with fine needle aspiration cytology and histopothology along with immunohistochemistry. J Indian Med

Assoc

108: 833-836  2010

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